Ефремов Е.А., Касатонова Е.В. Актуальные и перспективные методы лечения идиопатического мужского бесплодия. Андрология и генитальная хирургия 2022;23(3):48–53.
DOI: 10.17650/2070-9781-2022-23-3-48-53
Ефремов Е.А., Касатонова Е.В., Красняк С.С. и др. Роль антиоксидантов в улучшении параметров эякулята и клинических исходов у бесплодных пар. Экспериментальная и клиническая урология 2017;2:61–5.
Louis J.F., Thoma M.E., Sørensen D.N. et al. The prevalence of couple infertility in the United States from a male perspective: evidence from a nationally representative sample. Andrology 2013;1(5):741–8.
DOI: 10.1111/j.2047-2927.2013.00110.x
Лебедев Г.С., Голубев Н.А., Шадеркин И.А. и др. Мужское бесплодие в Российской Федерации: статистические данные за 2000–2018 годы. Экспериментальная и клиническая урология 2019;4:4–12.
DOI: 10.29188/2222-8543-2019-11-4-4-12
Jungwirth А., Diemer T., Kopa Z. et al. Male infertility. EAU Guideline. 2020. Available at:https://uroweb.org/guideline/male-infertility/#8.
Hamada A., Esteves S.C., Nizza M., Agarwal A. Unexplained male infertility: diagnosis and management. Int Braz J Urol 2012;38(5):576–94.
DOI: 10.1590/s1677-55382012000500002
Esteves S.C., Agarwal A. Novel concepts in male infertility. Int Braz J Urol 2011;37(1):5–15.
DOI: 10.1590/s1677-55382011000100002
Esteves S.C., Agarwal A., Cho C.L., Majzoub A. A Strengths-Weaknesses-Opportunities-Threats (SWOT) analysis on the clinical utility of sperm DNA fragmentation testing in specific male infertility scenarios. Trans Androl Urol 2017;6(Suppl 4):S734–S60.
DOI: 10.21037/tau.2017.08.20
Santi D., Spaggiari G., Simoni M. Sperm DNA fragmentation index as a promising predictive tool for male infertility diagnosis and treatment management – meta-analyses. Reprod Biomed Online 2018;37(3):315–26.
DOI: 10.1016/j.rbmo.2018.06.023
Коршунов М.Н., Коршунова Е.С., Кызласов П.С. и др. Структурные нарушения хроматина сперматозоидов. Патофизиологические аспекты. Клиническая значимость. Вестник урологии 2021;9(1):95–104.
DOI: 10.21886/2308-6424-2021-9-1-95-104
Gill K., Jakubik J., Rosiak-Gill A. et al. Utility and predictive value of human standard semen parameters and sperm DNA dispersion for fertility potential. Int J Environ Res Public Health 2019;16(11):2004.
DOI: 10.3390/ijerph16112004
Dada R. Sperm DNA damage diagnostics: when and why. Transl Androl Urol 2017;6(Suppl 4):S691–S4.
DOI: 10.21037/tau.2017.05.26
Esteves S.C., Zini A., Coward R.M. et al. Sperm DNA fragmentation testing: summary evidence and clinical practice recommendations. Andrologia 2021;53(2):e13874.
DOI: 10.1111/and.13874
Руднева С.А., Брагина Е.Е., Арифулин Е.А. и др. Фрагментация ДНК в сперматозоидах и ее взаимосвязь с нарушением сперматогенеза. Андрология и генитальная хирургия 2014;15(4):26–33.
DOI: 10.17650/2070-9781-2014-4-26-33
Авадиева Н.Э. Применение ДНК фрагментации спермы в андрологической практике. Вестник урологии 2019;7(1):7–11.
DOI: 10.21886/2308-6424-2019-7-1-7-11
Cho C.L., Agarwal A., Majzoub A., Esteves S.C. Clinical utility of sperm DNA fragmentation testing: concise practice recommendations. Transl Androl Urol 2017;6(Suppl 4):S366–S73.
DOI: 10.21037/tau.2017.07.28
Esteves S.C., Santi D., Simoni M. An update on clinical and surgical interventions to reduce sperm DNA fragmentation in infertile men. Andrology 2020;8(1):53–81.
DOI: 10.1111/andr.12724
Boeri L., Capogrosso P., Ventimiglia E. et al. Heavy cigarette smoking and alcohol consumption are associated with impaired sperm parameters in primary infertile men. Asian J Androl 2019;21(5):478–85.
DOI: 10.4103/aja.aja_110_18
Sharma R., Harlev A., Agarwal A., Esteves S.C. Cigarette smoking and semen quality: a new meta-analysis examining the effect of the 2010 World Health Organization laboratory methods for the examination of human semen. Eur Urol 2016;70(4):635–45.
DOI: 10.1016/j.eururo.2016.04.010
Mostafa R.M., Nasrallah Y.S., Hassan M.M. et al. The effect of cigarette smoking on human seminal parameters, sperm chromatin structure and condensation. Andrologia 2018;50(3):e12910.
DOI: 10.1111/and.12910
Fraga C.G., Motchnik P.A., Wyrobek A.J. et al. Smoking and low antioxidant levels increase oxidative damage to sperm DNA. Mutat Res 1996;351(2):199–203.
DOI: 10.1016/0027-5107(95)00251-0
Gunes S., Metin Mahmutoglu A., Arslan M.A., Henkel R. Smokinginduced genetic and epigenetic alterations in infertile men. Andrologia 2018;50(9):e13124.
DOI: 10.1111/and.13124
Ranganathan P., Rao K.A., Thalaivarasai Balasundaram S. Deterioration of semen quality and sperm-DNA integrity as influenced by cigarette smoking in fertile and infertile human male smokers – a prospective study. J Cell Biochem 2019;120(7):11784–93.
DOI: 10.1002/jcb.28458
Vande Loock K., Ciardelli R., Decordier I. et al. Preterm newborns show slower repair of oxidative damage and paternal smoking associated DNA damage. Mutagenesis 2012;27(5):573–80.
DOI: 10.1093/mutage/ges022
Aboulmaouahib S., Madkour A., Kaarouch I. et al. Impact of alcohol and cigarette smoking consumption in male fertility potential: looks at lipid peroxidation, enzymatic antioxidant activities and sperm DNA damage. Andrologia 2018;50(3):e12926.
DOI: 10.1111/and.12926
Lee K.M., Ward M.H., Han S. et al. Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk. Leuk Res 2009;33(2):250–58.
DOI: 10.1016/j.leukres.2008.06.031
Kumar S.B., Chawla B., Bisht S. et al. Tobacco use increases oxidative DNA damage in sperm – possible etiology of childhood cancer. Asian Pac J Cancer Prev 2015;16(16):6967–72.
DOI: 10.7314/apjcp.2015.16.16.6967
Verhaeghe F., Di Pizio P., Bichara C. et al. Cannabis consumption might exert deleterious effects on sperm nuclear quality in infertile men. Reprod Biomed Online 2020;40(2):270–80.
DOI: 10.1016/j.rbmo.2019.11.002
Radwan M., Jurewicz J., Merecz-Kot D. et al. Sperm DNA damage-the effect of stress and everyday life factors. Int J Impot Res 2016;28(4):148–54.
DOI: 10.1038/ijir.2016.15
Schmid T.E., Eskenazi B., Baumgartner A. et al. The effects of male age on sperm DNA damage in healthy non-smokers. Hum Reprod 2007;22(1):180–7.
DOI: 10.1093/humrep/del338
Jurewicz J., Hanke W., Radwan M., Bonde J.P. Environmental factors and semen quality. Int J Occup Med Environ Health 2009;22(4):305–29.
DOI: 10.2478/v10001-009-0036-1
Lafuente R., García-Blàquez N., Jacquemin B., Checa M.A. Outdoor air pollution and sperm quality. Fertil Steril 2016;106(4):880– 96.
DOI: 10.1016/j.fertnstert.2016.08.022
Radwan M., Jurewicz J., Polańska K. et al. Exposure to ambient air pollution – does it affect semen quality and the level of reproductive hormones? Ann Hum Biol 2016;43(1):50–6.
DOI: 10.3109/03014460.2015.1013986
Rubes J., Selevan S.G., Evenson D.P. et al. Episodic air pollution is associated with increased DNA fragmentation in human sperm without other changes in semen quality. Hum Reprod 2005;20(10):2776–83.
DOI: 10.1093/humrep/dei122
Jeng H.A., Pan C.H., Chao M.R. et al. Sperm quality and DNA integrity of coke oven workers exposed to polycyclic aromatic hydrocarbons. Int J Occup Med Environ Health 2016;29(6):915–26.
DOI: 10.13075/ijomeh.1896.00598
Rubes J., Selevan S.G., Sram R.J. et al. GSTM1 genotype influences the susceptibility of men to sperm DNA damage associated with exposure to air pollution. Mutat Res 2007;625(1–2):20–8.
DOI: 10.1016/j.mrfmmm.2007.05.012
Evenson D.P., Wixon R.L. Environmental toxicants cause sperm DNA fragmentation as detected by the Sperm Chromatin Structure Assay (SCSA®). Toxicol Appl Pharmacol 2005;207(2 Suppl);532–7.
DOI: 10.1016/j.taap.2005.03.021
Jamal F., Haque Q.S., Singh S., Rastogi S.K. The influence of organophosphate and carbamate on sperm chromatin and reproductive hormones among pesticide sprayers. Toxicol Ind Health 2016;32(8):1527–36.
DOI: 10.1177/0748233714568175
Miranda-Contreras L., Cruz I., Osuna J.A. et al.. Invest Clin 2015;56(2):123–36.
Sánchez-Peña L.C., Reyes B.E., López-Carrillo L. et al. Organophosphorous pesticide exposure alters sperm chromatin structure in Mexican agricultural workers. Toxicol Appl Pharmacol 2004;196(1):108–13.
DOI: 10.1016/j.taap.2003.11.023
Gandhi J., Hernandez R.J., Chen A. et al. Impaired hypothalamicpituitary-testicular axis activity, spermatogenesis, and sperm function promote infertility in males with lead poisoning. Zygote 2017;25(2):103–10.
DOI: 10.1017/S0967199417000028
Zhou D.D., Hao J.L., Guo K.M. et al. Sperm quality and DNA damage in men from Jilin Province, China, who are occupationally exposed to ionizing radiation. Genet Mol Res 2016;15(1):gmr.15018078.
DOI: 10.4238/gmr.15018078
Zhu W.J., Qiao J.. Zhonghua Nan Ke Xue 2015;21(11):1026–30.
Jurewicz J., Hanke W. Exposure to phthalates: reproductive outcome and children health. A review of epidemiological studies. Int J Occup Med Environ Health 2011;24(2):115–41.
DOI: 10.2478/s13382-011-0022-2
Bujan L., Walschaerts M., Brugnon F. et al. Impact of lymphoma treatments on spermatogenesis and sperm deoxyribonucleic acid: a multicenter prospective study from the CECOS network. Fertil Steril 2014;102(3):667–74.e.3.
DOI: 10.1016/j.fertnstert.2014.06.008
O’Flaherty C., Vaisheva F., Hales B.F. et al. Characterization of sperm chromatin quality in testicular cancer and Hodgkin’s lymphoma patients prior to chemotherapy. Hum Reprod 2008;23(5):1044–52.
DOI: 10.1093/humrep/den081
Smit M., van Casteren N.J., Wildhagen M.F. et al. Sperm DNA integrity in cancer patients before and after cytotoxic treatment. Hum Reprod 2010;18(8):77–83.
DOI: 10.1093/humrep/deq104
Ståhl O., Eberhard J., Jepson K. et al. Sperm DNA integrity in testicular cancer patients. Hum Reprod 2006;21(12):3199–205.
DOI: 10.1093/humrep/del292
Корнеев И.А., Мацуева И.А. Мужское бесплодие, метаболический синдром и ожирение. Урологические ведомости 2021;11(2):153–62.
DOI: 10.17816/uroved61509
Faure C., Dupont C., Baraibar M.A. et al. In subfertile couple, abdominal fat loss in men is associated with improvement of sperm quality and pregnancy: a case-series. PLoS One 2014;9(2):e86300.
DOI: 10.1371/journal.pone.0086300
Jurewicz J., Radwan M., Sobala W. et al. Dietary patterns and their relationship with semen quality. Am J Mens Health 2018;12(3):575–83.
DOI: 10.1177/1557988315627139
Morrison C.D., Brannigan R.E. Metabolic syndrome and infertility in men. Best Pract Res Clin Obstet Gynaecol 2015;29(4):507–15.
DOI: 10.1016/j.bpobgyn.2014.10.006
Sharma R., Agarwal A., Harlev A., Esteves S.C. A meta-analysis to study the effects of body mass index on sperm DNA fragmentation index in reproductive age men. Fertil Steril 2017;108(3):e138–e9.
DOI: 10.1016/j.fertnstert.2017.07.417
Cho C.L., Esteves S.C., Agarwal A. Novel insights into the pathophysiology of varicocele and its association with reactive oxygen species and sperm DNA fragmentation. Asian J Androl 2016;18(2):186–93.
DOI: 10.4103/1008-682X.170441
Agarwal A., Hamada A., Esteves S.C. Insight into oxidative stress in varicocele-associated male infertility: part 1. Nat Rev Urol 2012;9(12):678–90.
DOI: 10.1038/nrurol.2012.197
Hamada A., Esteves S.C., Agarwal A. Insight into oxidative stress in varicocele associated male infertility: part 2. Nat Rev Urol 2013;10(1):26–37.
DOI: 10.1038/nrurol.2012.198
Zini A., Dohle G. Are varicoceles associated with increased deoxyribonucleic acid fragmentation? Fertil Steril 2011;96(6):1283–7.
DOI: 10.1016/j.fertnstert.2011.10.016
Esteves S.C., Gosálvez J., López-Fernández C. et al. Diagnostic accuracy of sperm DNA degradation index (DDSi) as a potential noninvasive biomarker to identify men with varicocele-associated infertility. Int Urol Nephrol 2015;47(9):1471–7.
DOI: 10.1007/s11255-015-1053-6
Lira Neto F.T., Roque M., Esteves S.C. Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis. Fertil Steril 2021;116(3): 696–712.
DOI: 10.1016/j.fertnstert.2021.04.003
Roque M., Esteves S.C. Effect of varicocele repair on sperm DNA fragmentation: а review. Int Urol Nephrol 2018;50(4):583–603.
DOI: 10.1007/s11255-018-1839-4
Cantoro U., Polito M., Muzzonigro G. Reassessing the role of subclinical varicocele in infertile men with impaired semen quality: a prospective study. Urology 2015;85(4):826–30.
DOI: 10.1016/j.urology.2015.01.015
Kim H.J., Seo J.T., Kim K.J. et al. Clinical significance of subclinical varicocelectomy in male infertility: systematic review and metaanalysis. Andrologia 2016;48(6):654–61.
DOI: 10.1111/and.12495
García-Peiró A., Ribas-Maynou J., Oliver-Bonet M. et al. Multiple determinations of sperm DNA fragmentation show that varicocelectomy is not indicated for infertile patients with subclinical varicocele. BioMed Res Int 2014;2014:181396.
DOI: 10.1155/2014/181396
Ni K., Steger K., Yang H. et al. A comprehensive investigation of sperm DNA damage and oxidative stress injury in infertile patients with subclinical, normozoospermic, and astheno/oligozoospermic clinical varicocele. Andrology 2016;4(5):816–24.
DOI: 10.1111/andr.12210
Agarwal A., Rana M., Qiu E. et al. Role of oxidative stress, infection and inflammation in male infertility. Andrologia 2018;50(11):e13126.
DOI: 10.1111/and.13126
Боровец С.Ю., Рыбалов М.А., Горбачев А.Г., Аль-Шукри С.Х. Влияние препарата «Простатилен® АЦ» на фрагментацию ДНК сперматозоидов при лечении пациентов с хроническим абактериальным простатитом и сопутствующими нарушениями репродуктивной функции. Андрология и генитальная хирургия 2017;18(3):54–8.
DOI: 10.17650/2070-9781-2017- 18-3-54-58
Рогозин Д.С. Мужская фертильность: обзор литературы января – марта 2021 года. Вестник урологии 2021;9(2):142–9.
DOI: 10.21886/2308-6424-2021-9-2-142-149
Buck Louis G.M., Sundaram R., Schisterman E.F. et al. Semen quality and time to pregnancy: the longitudinal investigation of fertility and the environment study. Fertil Steril 2014;101(2):453–62.
DOI: 10.1016/j.fertnstert.2013.10.022
Carlini T., Paoli D., Pelloni M. et al. Sperm DNA fragmentation in Italian couples with recurrent pregnancy loss. Reprod Biomed Online 2017;34(1):58–65.
DOI: 10.1016/j.rbmo.2016.09.014
Рыжков А.И., Шорманов И.С., Соколова С.Ю. Фрагментация ДНК сперматозоидов. Есть ли связь с основными параметрами спермы и возрастом? Экспериментальная и клиническая урология 2020;4:58–64.
DOI: 10.29188/2222-8543-2020-13-4-58-64
Evenson D.P., Djira G., Kasperson K., Christianson J. Relationships between the age of 25,445 men attending infertility clinics and sperm chromatin structure assay (SCSA®) defined sperm DNA and chromatin integrity. Fertil Steril 2020;114(2):311–20.
DOI: 10.1016/j.fertnstert.2020.03.028
Sakkas D., Alvarez J.G. Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis. Fertil Steril 2010;93(4):1027–36.
DOI: 10.1016/j.fertnstert.2009.10.046
Rima D., Shiv B.K., Bhavna C. et al. Oxidative stress induced damage to paternal genome and impact of meditation and yoga – can it reduce incidence of childhood cancer? Asian Pac J Cancer Prev 2016;17(9):4517–25.
De Iuliis G.N., Thomson L.K., Mitchell L.A. et al. DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2’-deoxyguanosine, a marker of oxidative stress. Biol Reprod 2009;81(3): 517–24.
DOI: 10.1095/biolreprod.109.076836
Muratori M., Tamburrino L., Marchiani S. et al. Investigation on the origin of sperm DNA fragmentation: role of apoptosis, immaturity and oxidative stress. Mol Med 2015;21(1):109–22.
DOI: 10.2119/molmed.2014.00158
Agarwal A., Parekh N., Panner Selvam M.K. et al. Male Oxidative Stress Infertility (MOSI): proposed terminology and clinical practice guidelines for management of idiopathic male infertility. World J Mens Health 2019;37(3):296–312.
DOI: 10.5534/wjmh.190055
Chengyong W., Man Y., Mei L. et al. GSTM1 null genotype contributes to increased risk of male infertility: a meta-analysis. J Assist Reprod Genet 2012;29(8):837–45.
DOI: 10.1093/humrep/del338
Majzoub A., Agarwal A., Esteves S.C. Understanding sperm DNA fragmentation. Trans Androl Urol 2017;6(Suppl 4):S535–S8.
DOI: 10.21037/tau.2017.04.27
Champroux A., Torres-Carreira J., Gharagozloo P. et al. Mammalian sperm nuclear organization: resiliencies and vulnerabilities. Basic Clin Androl 2016;26:17.
DOI: 10.1186/s12610-016-0044-5
Gosálvez J., López-Fernández C., Fernández J.L. et al. Unpacking the mysteries of sperm DNA fragmentation: ten frequently asked questions. J Rep Biotech Fertil 2015;4.
DOI: 10.1177/2058915815594454
Oleszczuk K., Augustinsson L., Bayat N. et al. Prevalence of high DNA fragmentation index in male partners of unexplained infertile couples. Andrology 2013;1(3):357–60.
DOI: 10.1111/j.2047-2927.2012.00041.x
ESHRE Guideline Group on RPL, Bender Atik R., Christiansen O.B., Elson J. et al. ESHRE guideline: recurrent pregnancy loss. Hum Reprod Open 2018;2018(2):hoy004.
DOI: 10.1093/hropen/hoy004
Robinson L., Gallos I.D., Conner S.J. et al. The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis. Hum Reprod Open 2012;27(10):2908–17.
DOI: 10.1093/humrep/des261
McQueeni D.B., Zhang J., Robins J.C. Sperm DNA fragmentation and recurrent pregnancy loss: a systematic review and metaanalysis. Fertil Steril 2019;112(1):54–60.e3.
DOI: 10.1016/j.fertnstert.2019.03.003
Tan J., Taskin O., Albert A., Bedaiwy M.A. Association between sperm DNA fragmentation and idiopathic recurrent pregnancy loss: a systematic review and meta-analysis. Reprod Biomed Online 2019;38(6):951–60.
DOI: 10.1016/j.rbmo.2018.12.029
Zidi-Jrah I., Hajlaoui A., Mougou-Zerelli S. et al. Relationship between sperm aneuploidy, sperm DNA integrity, chromatin packaging, traditional semen parameters, and recurrent pregnancy loss. Fertil Steril 2016;105(1):58–64.
DOI: 10.1016/j.fertnstert.2015.09.041
Ribas-Maynou J., Benet J. Single and double strand sperm DNA damage: different reproductive effects on male fertility. Genes (Basel) 2019;10(2):105.
DOI: 10.3390/genes10020105
Vandekerckhove F.W., De Croo I., Gerris J. et al. Sperm chromatin dispersion test before sperm preparation is predictive of clinical pregnancy in cases of unexplained infertility treated with intrauterine insemination and induction with clomiphene citrate. Front Med 2016;3:63.
DOI: 10.3389/fmed.2016.00063
Chen Q., Zhao J.Y., Xue X., Zhu G.X. The association between sperm DNA fragmentation and reproductive outcomes following intrauterine insemination, a meta-analysis. Reprod Toxicol 2019;86:50–5.
DOI: 10.1016/j.reprotox.2019.03.004
Боровец С.Ю., Аль-Шукри С.Х., Белоусов В.Я. Прогностическая значимость фрагментации ДНК сперматозоидов в отношении исходов вспомогательных репродуктивных технологий. Урологические ведомости 2015;5(1):39.
DOI: 10.17816/uroved5139-39
Sugihara A., Van Avermaete F., Roelant E. et al. The role of sperm DNA fragmentation testing in predicting intra-uterine insemination outcome: a systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol 2020;244:8–15.
DOI: 10.1016/j.ejogrb.2019.10.005
Zhao J., Zhang Q., Wang Y., Li Y. Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: а systematic review and meta-analysis. Fertil Steril 2014;102:998–1005. e1008.
DOI: 10.1016/j.fertnstert.2014.06.033
Xie P., Keating D., Parrella A. et al. Sperm genomic integrity by TUNEL varies throughout the male genital tract. J Urol 2020;203(4):802–8.
DOI: 10.1097/JU.0000000000000659
Gawecka J.E., Boaz S., Kasperson K. et al. Luminal fluid of epididymis and vas deferens contributes to sperm chromatin fragmentation. Hum Reprod 2015;30(12):2725–36.
DOI: 10.1093/humrep/dev245
Ambar R.F., Agarwal A., Majzoub A. et al. The use of testicular sperm for intracytoplasmic sperm injection in patients with high sperm DNA damage: a systematic review. World J Mens Health 2020;39(3):391–8.
DOI: 10.5534/wjmh.200084
Коршунов М.Н., Коршунова Е.С., Даренков С.П. Способ лечения мужского бесплодия при высоком показателе ДНК-фрагментации эякуляторных сперматозоидов. Патент RU 2685797C1 от 23.04.2019.
Aitken R.J. DNA damage in human spermatozoa; important contributor to mutagenesis in the offspring. Trans Androl Urol 2017;6(Suppl 4):S761–S4.
DOI: 10.21037/tau.2017.09.13
Bungum M., Bungum L., Lynch K.F. et al. Spermatozoa DNA damage measured by sperm chromatin structure assay (SCSA) and birth characteristics in children conceived by IVF and ICSI. Int J Androl 2012;35(4):485–90.
DOI: 10.1111/j.1365-2605.2011.01222.x
Koppen G., Azqueta A., Pourrut B. et al. The next three decades of the comet assay: a report of the 11th International Comet Assay Workshop. Mutagenesis 2017;32(3):397–408.
DOI: 10.1093/mutage/gex002
Sharma R.K., Sabanegh E., Mahfouz R. et al. TUNEL as a test for sperm DNA damage in the evaluation of male infertility. Urology 2010;76(6):1380–6.
DOI: 10.1016/j.urology.2010.04.036
Feijó C.M., Esteves S.C. Diagnostic accuracy of sperm chromatin dispersion test to evaluate sperm deoxyribonucleic acid damage in men with unexplained infertility. Fertil Steril 2014;101(1):58–63.e3.
DOI: 10.1016/j.fertnstert.2013.09.002
Pratap H., Hottigoudar S.Y., Nichanahalli K.S., Chand P. Assessment of sperm deoxyribose nucleic acid fragmentation using sperm chromatin dispersion assay. J Pharmacol Pharmacother 2017;8(2):45–9.
DOI: 10.4103/jpp.JPP_187_16
Evenson D.P. Sperm Chromatin Structure Assay (SCSA(®)) and other sperm DNA fragmentation tests for evaluation of sperm nuclear DNA integrity as related to fertility. Anim Reprod Sci 2016;169:56–75.
DOI: 10.1016/j.anireprosci.2016.01.017
Majzoub A., Agarwal A., Cho C.L., Esteves S.C. Sperm DNA fragmentation testing: a cross sectional survey on current practices of fertility specialists. Transl Androl Urol 2017;6(Suppl 4):S710–S9.
DOI: 10.21037/tau.2017.06.21
Dahan M.H., Mills G., Khoudja R. et al. Three hour abstinence as a treatment for high sperm DNA fragmentation: a prospective cohort study. J Assist Reprod Genet 2021;38(1):227–33.
DOI: 10.1007/s10815-020-01999-w
Esteves S.C. Interventions to prevent sperm DNA damage effects on reproduction. Adv Exp Med Biol 2019;1166:119–48.
DOI: 10.1007/978-3-030-21664-1_8
Pini T., Makloski R., Maruniak K. et al. Mitigating the effects of oxidative sperm DNA damage. Antioxidants (Basel) 2020;9(7):589.
DOI: 10.3390/antiox9070589
Kopa Z., Keszthelyi M., Sofikitis N. Administration of antioxidants in the infertile male: when it may have a beneficial effect? Curr Pharm Des 2020;27(23):2665–8.
DOI: 10.2174/1381612826666200303115552
Гамидов С.И., Овчинников Р.И., Попова А.Ю. и др. Адъювантная антиоксидантная терапия у больных бесплодием при варикоцеле. Урология 2017;2(Suppl):64–72.
DOI: 10.18565/urol.2017.2-supplement.64-72
Gual-Frau J., Abad C., Amengual M.J. et al. Oral antioxidant treatment partly improves integrity of human sperm DNA in infertile grade I varicocele patients. Hum Fertil (Camb) 2015;18(3):225–9.
DOI: 10.3109/14647273.2015.1050462
Colacurci N., De Leo V., Ruvolo G. et al. Recombinant FSH improves sperm DNA damage in male infertility: a phase II clinical trial. Front Endocrinol (Lausanne) 2018;9:383.
DOI: 10.3389/fendo.2018.00383