Szalontai K., Gémes N., Furák J., Varga T., Neuperger P., Balog J.Á. et al. Chronic Obstructive Pulmonary Disease: Epidemiology, Biomarkers, and Paving the Way to Lung Cancer. J Clin Med. 2021;10(13):2889. https://doi.org/10.3390/jcm10132889..
DOI: 10.3390/jcm10132889
Wilkinson T.M., Hurst J.R., Perera W.R., Willks M., Donaldson G.C., Wedzicha J.A. Effect of interactions between lower airway bacterial and rhinoviral infection in exacerbations of COPD. Chest. 2006;129(2):317–324. https://doi.org/10.1378/chest.129.2.317..
DOI: 10.1378/chest.129.2.317
George S.N., Garcha D.S., Mackay A.J., Patel A.R.C., Singh R., Sapsford R.J. et al. Human rhinovirus infection during naturally occurring COPD exacerbations. Eur Respir J. 2014;44(1):87–96. https://doi.org/10.1183/09031936.00223113..
DOI: 10.1183/09031936.00223113
Bafadhel M., McKenna S., Terry S., Mistry V., Reid C., Haldar P. et al. Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers. Am J Respir Crit Care Med. 2011;184(6):662–671. https://doi.org/10.1164/rccm.201104-0597oc..
DOI: 10.1164/rccm.201104-0597oc
Smith J.C., Sausville E.L., Girish V., Yuan M.L., Vasudevan A., John K.M., Sheltzer J.M. Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract. Dev Cell. 2020;53(5):514.e3–529.e3. https://doi.org/10.1016/j.devcel.2020.05.012..
DOI: 10.1016/j.devcel.2020.05.012
Kasahara Y., Tuder R.M., Cool C.D., Lynch D.A., Flores S.C., Voelkel N.F. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med. 2001;163(3 Pt. 1):737–744. https://doi.org/10.1164/ajrccm.163.3.2002117..
DOI: 10.1164/ajrccm.163.3.2002117
Minakata Y., Nakanishi M., Hirano T., Matsunaga K., Yamagata T., Ichinose M. Microvascular hyperpermeability in COPD airways. Thorax. 2005;60(10):882. https://doi.org/10.1136/thx.2005.045765..
DOI: 10.1136/thx.2005.045765
Vaidyula V.R., Criner G.J., Grabianowski C., Rao A.K. Circulating tissue factor procoagulant activity is elevated in stable moderate to severe chronic obstructive pulmonary disease. Thromb Res. 2009;124(3):259–261. https://doi.org/10.1016/j.thromres.2008.12.030..
DOI: 10.1016/j.thromres.2008.12.030
Halpin D.M.G., Singh D., Hadfield R.M. Inhaled corticosteroids and COVID-19: a systematic review and clinical perspective. Eur Respir J. 2020;55(5):2001009. https://doi.org/10.1183/13993003.01009-2020..
DOI: 10.1183/13993003.01009-2020
Bartoletti M., Giannella M., Scudeller L., Tedeschi S., Rinaldi M., Bussini L. et al. Predictors of severe respiratory failure in hospitalized patients with SARS-CoV-2 infection: development and validation of a prediction model (PREDI-CO study). Clin Microbiol Infect. 2020;26(11):1545–1553. https://doi.org/10.1016/j.cmi.2020.08.003..
DOI: 10.1016/j.cmi.2020.08.003
Palmieri L., Vanacore N., Donfrancesco C., Lo Noce C., Canevelli M., Punzo O. et al. Clinical Characteristics of Hospitalized Individuals Dying With COVID-19 by Age Group in Italy. J Gerontol A Biol Sci Med Sci. 2020;75(9):1796–1800. https://doi.org/10.1093/gerona/glaa146..
DOI: 10.1093/gerona/glaa146
He Y., Xie M., Zhao J., Liu X. Clinical Characteristics and Outcomes of Patients with Severe COVID-19 and Chronic Obstructive Pulmonary Disease (COPD). Med Sci Monit. 2020;26:e927212. https://doi.org/10.12659/msm.927212..
DOI: 10.12659/msm.927212
Петрова Д.В., Рудакова Д.М., Реуцкая Е.М., Петаева Е.М., Соснова О.Л., Михель С.Д. и др. Опыт применения ингаляционного гипертонического раствора с гиалуроновой кислотой у пациентов с хронической обструктивной болезнью легких. Практическая пульмонология. 2016;(4):65–69. Режим доступа: http://www.atmosphere-ph.ru/modules/Magazines/articles/pulmo/pp_4_2016_65.pdf.http://www.atmosphere-ph.ru/modules/Magazines/articles/pulmo/pp_4_2016_65.pdf
Петрова Д.В., Рудакова Д.М., Реуцкая Е.М., Петаева Е.М., Соснова О.Л., Михель С.Д. и др. Опыт применения ингаляционного гипертонического раствора с гиалуроновой кислотой у пациентов с хронической обструктивной болезнью легких. Практическая пульмонология. 2016;(4):65–69. Режим доступа: http://www.atmosphere-ph.ru/modules/Magazines/articles/pulmo/pp_4_2016_65.pdf.http://www.atmosphere-ph.ru/modules/Magazines/articles/pulmo/pp_4_2016_65.pdf
Симонова О.И., Горинова Ю.В. Новая форма гипертонического раствора для небулайзерной терапии. Вопросы современной педиатрии. 2016;15(6):631–634. https://doi.org/10.15690/vsp.v15i6.1662..
DOI: 10.15690/vsp.v15i6.1662
Симонова О.И., Горинова Ю.В., Бакрадзе М.Д. Эффективность ингаляций гипертонического раствора у детей с бронхитами и бронхиолитами. Вопросы современной педиатрии. 2014;13(4):33–39. https://doi.org/10.15690/vsp.v13i4.1082..
DOI: 10.15690/vsp.v13i4.1082
Красовский С.А., Амелина Е.Л., Черняк А.В., Кондратьева Е.И., Горинова Ю.В., Зоненко О.Г. и др. Наблюдательное исследование по использованию комбинированного раствора 7[%] раствора натрия хлорида и 0,1[%] гиалуроновой кислоты у взрослых больных муковисцидозом. Медицинский совет. 2018;(21):72–77. https://doi.org/10.21518/2079-701X-2018-21-72-77..
DOI: 10.21518/2079-701X-2018-21-72-77
Graeber S.Y., Zhou-Suckow Z., Schatterny J., Hirtz S., Boucher R.C., Mall M.A. Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease. Am J Respir Cell Mol Biol. 2013;49(3):410–417. https://doi.org/10.1165/rcmb.2013-0050oc..
DOI: 10.1165/rcmb.2013-0050oc
Robinson M., Hemming A.L., Regnis J.A., Wong A.G., Bailey D.L., Bautovich G.J. et al. Effect of increasing doses of hypertonic saline on mucociliary clearance in patients with cystic fibrosis. Thorax. 1997;52(10):900–903. https://doi.org/10.1136/thx.52.10.900..
DOI: 10.1136/thx.52.10.900
Henke M.O., Ratjen F. Mucolytics in cystic fibrosis. Paediatr Respir Rev. 2007;8(1):24–29. https://doi.org/10.1016/j.prrv.2007.02.009..
DOI: 10.1016/j.prrv.2007.02.009
King M., Dasgupta B., Tomkiewicz R.P., Brown N.E. Rheology of cystic fibrosis sputum after in vitro treatment with hypertonic saline alone and in combination with recombinant human deoxyribonuclease I. Am J Respir Crit Care Med. 1997;156(1):173–177. https://doi.org/10.1164/ajrccm.156.1.9512074..
DOI: 10.1164/ajrccm.156.1.9512074
Rodwell L.T., Anderson S.D. Airway responsiveness to hyperosmolar saline challenge in cystic fibrosis: a pilot study. Pediatr Pulmonol. 1996;21(5):282–289. https://doi.org/10.1002/(sici)1099-0496(199605)21:5[%]3C282::aid-ppul3[%]3E3.0.co;2-p..
DOI: 10.1002/(sici)1099-0496(199605)21:5[%]3C282::aid-ppul3[%]3E3.0.co;2-p
Rodwell L.T., Anderson S.D. Airway responsiveness to hyperosmolar saline challenge in cystic fibrosis: a pilot study. Pediatr Pulmonol. 1996;21(5):282–289. https://doi.org/10.1002/(sici)1099-0496(199605)21:5[%]3C282::aid-ppul3[%]3E3.0.co;2-p..
DOI: 10.1002/(sici)1099-0496(199605)21:5[%]3C282::aidppul3[%]3E3.0.co;2-p
Donaldson S.H., Bennett W.D., Zeman K.L., Knowles M.R., Tarran R., Boucher R.C. Mucus clearance and lung function in cystic fibrosis with hypertonic saline. N Engl J Med. 2006;354(3):241–250. https://doi.org/10.1056/nejmoa043891..
DOI: 10.1056/nejmoa043891
Goralski J.L., Wu D., Thelin W.R., Boucher R.C., Button B. The in vitro effect of nebulised hypertonic saline on human bronchial epithelium. Eur Respir J. 2018;51(5):1702652. https://doi.org/10.1183/13993003.02652-2017..
DOI: 10.1183/13993003.02652-2017
Smyth A.R., Bell S.C., Bojcin S., Bryon M., Duff A., Flume P. et al. European Cystic Fibrosis Society Standards of Care: Best Practice guidelines. J Cyst Fibros. 2014;13(1 Suppl.):S23–S42. https://doi.org/10.1016/j.jcf.2014.03.010..
DOI: 10.1016/j.jcf.2014.03.010
Gao P., Gibson P.G., Zhang J., He X., Hao Y., Li P., Liu H. The safety of sputum induction in adults with acute exacerbation of COPD. Clin Respir J. 2013;7(1):101–109. https://doi.org/10.1111/j.1752-699x.2012.00291.x..
DOI: 10.1111/j.1752-699x.2012.00291.x
Allegra L., Della Patrona S., Petrigni G. Hyaluronic acid: perspectives in lung diseases. Handb Exp Pharmacol. 2012;(207):385–401. https://doi.org/10.1007/978-3-642-23056-1_17..
DOI: 10.1007/978-3-642-23056-1_17
Máiz Carro L., Martínez-García MA. Use of Hyaluronic Acid (HA) in Chronic Airway Diseases. Cells. 2020;9(10):2210. https://doi.org/10.3390/cells9102210..
DOI: 10.3390/cells9102210
Buonpensiero P., De Gregorio F., Sepe A., Di Pasqua A., Ferri P., Siano M. et al. Hyaluronic acid improves “pleasantness” and tolerability of nebulized hypertonic saline in a cohort of patients with cystic fibrosis. Adv Ther. 2010;27(11):870–878. https://doi.org/10.1007/s12325-010-0076-8..
DOI: 10.1007/s12325-010-0076-8
Turino G.M., Cantor J.O. Hyaluronan in respiratory injury and repair. Am J Respir Crit Care Med. 2003;167(9):1169–1175. https://doi.org/10.1164/rccm.200205-449pp..
DOI: 10.1164/rccm.200205-449pp
Cantor J.O., Shteyngart B., Cerreta J.M., Liu M. The effect of hyaluronan on elastic fiber injury in vitro and elastase-induced airspace enlargement in vivo. Proc Soc Exp Biol Med. 2000;225(1):65–71. https://doi.org/10.1111/j.1525-1373.2000.22508.x..
DOI: 10.1111/j.1525-1373.2000.22508.x
Papakonstantinou E., Bonovolias I., Roth M., Tamm M., Schumann D., Baty F. et al. Serum levels of hyaluronic acid are associated with COPD severity and predict survival. Eur Respir J. 2019;53(3):1801183. https://doi.org/10.1183/13993003.01183-2018..
DOI: 10.1183/13993003.01183-2018
Papakonstantinou E., Roth M., Klagas I., Karakiulakis G., Tamm M., Stolz D. COPD exacerbations are associated with proinflammatory degradation of hyaluronic acid. Chest. 2015;148(6):1497–1507. https://doi.org/10.1378/chest.15-0153..
DOI: 10.1378/chest.15-0153
Cantor J.O., Cerreta J.M., Ochoa M., Ma S., Chow T., Grunig G., Turino G.M. Aerosolized hyaluronan limits airspace enlargement in a mouse model of cigarette smoke-induced pulmonary emphysema. Exp Lung Res. 2005;31(4):417–430. https://doi.org/10.1080/01902140590918669..
DOI: 10.1080/01902140590918669
Cantor J.O., Cerreta J.M., Ochoa M., Ma S., Liu M., Turino G.M. Therapeutic effects of hyaluronan on smoke-induced elastic fiber injury: Does delayed treatment affect efficacy? Lung. 2011;189(1):51–56. https://doi.org/10.1007/s00408-010-9271-2..
DOI: 10.1007/s00408-010-9271-2
Cantor J.O., Cerreta J.M., Armand G., Turino G.M. Aerosolized hyaluronic acid decreases alveolar injury induced by human neutrophil elastase. Proc Soc Exp Biol Med. 1998;217(4):471–475. https://doi.org/10.3181/00379727-217-44260..
DOI: 10.3181/00379727-217-44260
Авдеев С.Н., Адамян Л.В., Алексеева Е.И., Багненко С.Ф., Баранов А.А., Баранова Н.Н. и др. Временные методические рекомендации. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 11 (07.05.2021). М.; 2021. 225 с. Режим доступа: https://стопкоронавирус.рф/ai/doc/872/attach/Bmr_COVID-19_compressed.pdf.https://стопкоронавирус.рф/ai/doc/872/attach/Bmr_COVID-19_compressed.pdf
Авдеев С.Н., Адамян Л.В., Алексеева Е.И., Багненко С.Ф., Баранов А.А., Баранова Н.Н. и др. Временные методические рекомендации. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 11 (07.05.2021). М.; 2021. 225 с. Режим доступа: https://стопкоронавирус.рф/ai/doc/872/attach/Bmr_COVID-19_compressed.pdf.https://стопкоронавирус.рф/ai/doc/872/attach/Bmr_COVID-19_compressed.pdf
Чучалин А.Г., Авдеев С.Н., Айсанов З.Р., Белевский А.С., Лещенко И.В., Овчаренко С.И., Шмелев Е.И. Хроническая обструктивная болезнь легких: клинические рекомендации. М.; 2021. Режим доступа: https://cr.minzdrav.gov.ru/schema/603_2.https://cr.minzdrav.gov.ru/schema/603_2
Чучалин А.Г., Авдеев С.Н., Айсанов З.Р., Белевский А.С., Лещенко И.В., Овчаренко С.И., Шмелев Е.И. Хроническая обструктивная болезнь легких: клинические рекомендации. М.; 2021. Режим доступа: https://cr.minzdrav.gov.ru/schema/603_2.https://cr.minzdrav.gov.ru/schema/603_2